Body Protection Compound
5mg / vial
BPC-157 is a 15-amino acid peptide fragment derived from a protein found in gastric juice. It is one of the most extensively studied compounds in the peptide research space — with a broad range of investigated applications spanning gut health, tendon and ligament repair, and systemic anti-inflammatory effects.
BPC-157 (Body Protection Compound 157) is a partial sequence of the body protection compound found naturally in human gastric juice. It is stable, resistant to enzymatic degradation, and has been studied in numerous in-vitro and animal models since the early 1990s. Its sequence is: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, with a molecular weight of 1419.5 g/mol. Unlike many peptides, BPC-157 demonstrates exceptional stability — it does not require a cold chain during transit and is resistant to breakdown in gastric environments, which has made it a particularly practical compound for research.
Research suggests BPC-157 operates through multiple interconnected pathways. It appears to upregulate VEGF (vascular endothelial growth factor) signalling, promoting angiogenesis — the formation of new blood vessels — which is critical to tissue repair. In tendon and ligament models, it has been observed to accelerate fibroblast migration and collagen synthesis through modulation of the FAK-paxillin pathway. BPC-157 also appears to modulate nitric oxide (NO) synthesis, which may underlie its observed effects on gastrointestinal mucosal healing. Additionally, research has identified interactions with the dopaminergic and serotonergic systems in CNS models, suggesting a broader systemic reach than its gastric origin might imply.
Peer-reviewed research has investigated BPC-157 in models of Achilles tendon repair, inflammatory bowel disease, bone healing, and systemic organ protection. Research originating from the University of Zagreb has formed the backbone of BPC-157 literature, with over 100 published studies across gastroenterology, orthopaedics, and neuroscience journals. Notable research areas include: tendon-to-bone healing acceleration, gut mucosal protection in NSAID-induced injury models, bone fracture repair, and liver fibrosis. Studies have also investigated its interactions with growth hormone and nitric oxide pathways, as well as its effects in models of traumatic brain injury and spinal cord damage.
Commonly researched with