Selective GHRP
5mg / vial
Ipamorelin is a pentapeptide and selective growth hormone releasing peptide (GHRP). It is widely regarded in research as the most selective GHRP available — stimulating growth hormone release with minimal observed effects on cortisol, prolactin, or appetite hormones that are commonly elevated by older GHRPs.
Unlike GHRP-6 or GHRP-2, Ipamorelin does not significantly stimulate ACTH or cortisol release. This selectivity makes it the GHRP of choice in research contexts where isolated GH pulse investigation is the objective, without the confounding variables introduced by stress hormone elevation.
Ipamorelin mimics ghrelin and binds to the GHS-R1a receptor on the pituitary, stimulating GH release. Its selectivity is attributed to its inability to stimulate other pituitary hormones at equivalent doses. When combined with CJC-1295 No DAC, the two peptides act synergistically on separate receptor pathways to amplify GH pulse magnitude.
Studies have examined Ipamorelin in contexts including GH deficiency models, bone density research, body composition, and age-related GH decline. Its clean receptor profile makes it the most frequently referenced GHRP in contemporary research literature.
Commonly researched with