Thymosin Beta-4 Fragment
5mg / vial
TB-500 is a synthetic fragment of Thymosin Beta-4 — a naturally occurring peptide found in virtually all human and animal cells. It is best known in research for its roles in tissue repair, wound healing, and cellular migration, and is frequently studied in combination with BPC-157.
Thymosin Beta-4 (Tβ4) is one of the most abundant peptides in mammalian tissue. TB-500 represents its active fragment — the actin-binding domain responsible for much of its biological activity. It was first isolated in the thymus but is now known to be expressed systemically.
TB-500's primary mechanism involves sequestering G-actin, regulating actin dynamics, and promoting cell migration. Research has demonstrated effects on endothelial cell and keratinocyte migration, new blood vessel formation, and reduction of inflammatory cytokines. It has been studied in cardiac, muscular, and dermal repair models.
Research has examined TB-500 in models of cardiac repair after infarction, tendon and muscle injury, corneal wound healing, and hair follicle stimulation. Frequently co-administered with BPC-157 in recovery-focused research protocols.
Commonly researched with